Supplemental Ubiquinol in Patients with Advanced Congestive Heart Failure

An initial group of subjects with end stage congestive heart failure (NYHA Class IV) were being given an average of 450 mg per day of Ubiquinone. Despite the supplemental Ubiquinone, blood values were a mean of 1.6 mcg/mL plasma.

Dr. Langsjoen changed subjects to the Ubiquinol form (average of 580 mg/day) and found blood values rose from 1.6 microg/ml up to 6.5 microg/ml. The researchers noted remarkable clinical improvement with NYHA class improving from a mean of IV to a mean of II, and mean Ejection Fraction improved from 22% (10-35%) up to 39% (10-60%).

Journal: Biofactors

Authors: Langsjoen PH, Langsjoen AM

Department: East Texas Medical Center and Trinity Mother Francis Hospital, TX, USA.

Abstract link: http://www.ncbi.nlm.nih.gov/pubmed/19096107

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